CLLS Stock Analysis

Cellectis SA
HEALTHCARE BIOTECHNOLOGY

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Strong Caution Mixed Weak Unavailable
StockValueFinder Grade
F
27.41 / 100
Weak
Confidence: High (80.0%) Coverage: 80.0%
Business Quality 5.5
Financial Strength 43.0
Earnings & Growth 33.8
Valuation 20.8
Market Strength 43.5
The grade combines Business Quality, Financial Strength, Earnings & Growth, Valuation, and Market Strength. Rating and Trend remain separate signals.
Rating AVOID
Avoid
The screening rules are warning against this setup.
Rating is the simple decision label from the screening rules.
Trend SELL / AVOID TREND
Weak Trend
The current trend is unfavorable.
Trend shows whether price action is helping or hurting the setup.
P/E Ratio -1.60
Not Meaningful
Negative or missing earnings make P/E hard to use.
P/E shows how much investors pay for each dollar of earnings.
ROIC -34.52%
Poor
Negative ROIC suggests capital is not being used profitably.
ROIC measures how efficiently capital turns into profit.
Debt Payback -1.21 yrs
Unavailable
Debt payback is unavailable or not meaningful.
Debt payback estimates how quickly debt could be covered.
Interest Coverage -4.08x
Poor
Negative coverage means earnings are not covering interest costs.
Interest coverage shows how easily earnings cover interest costs.
Price $0.98
Market Price
Price alone is not a buy or sell signal.
Price should be judged with valuation, quality, and trend.
Last updated: 2026-10-23 09:52:25

Performance Overview

Trailing adjusted-close returns as of 2026-07-02. Benchmark is SPY.

YTD Return

CLLS -31.82%
SPY +9.80%

1-Year Return

CLLS +100.00%
SPY +21.37%

3-Year Return

CLLS +67.73%
SPY +74.40%

5-Year Return

CLLS -78.23%
SPY +83.76%

Returns are calculated from adjusted close prices and may differ from broker or research-site totals depending on data source, dividend handling, benchmark choice, and latest available trading date.

Legacy Screening Checks

This page uses cached SQL data from the latest StockValueFinder scan, so it loads fast without hitting Alpha Vantage on every page view.

33%
EPS Strength
FAIL

Looks for positive and improving earnings per share.

ROIC 10%+
FAIL

Looks for strong return on invested capital.

Interest Coverage 6+
FAIL

Checks whether operating income comfortably covers interest expense.

Debt Payback ≤ 3 Years
PASS

Checks whether free cash flow could pay down long-term debt quickly.

P/E 15 or Less
PASS

Checks whether valuation is reasonable under the current rule set.

Moving Average Trend
SELL / AVOID TREND

Uses 20-day, 50-day, and 200-day moving averages for entry timing context.

A high StockValueFinder score is a research signal, not a guarantee. Strong companies can still fall during recessions, sector downturns, valuation resets, or company-specific events. Always review the business, risks, SEC filings, valuation, and your personal investment goals before buying.

Cached Technical Data

Moving average values from the latest stored scan.

20-Day MA1.24
50-Day MA2.14
200-Day MA3.17
MA Score0

Latest Published Stock Research

Research generated: October 23, 2026

CLLS Stock Analysis: Why Cellectis SA Scored 33% in Stock Value Finder

Understanding Cellectis SA (CLLS): A Detailed StockValueFinder Review

Overview of Cellectis SA (CLLS)

Cellectis SA (CLLS) is a clinical-stage biotechnology company operating in the healthcare sector, specifically within the biotechnology industry. The company focuses on developing immunotherapies, particularly chimeric antigen receptor (CAR) T-cell therapies, which are designed to treat various forms of cancer. As an educational review, this article examines CLLS through the lens of StockValueFinder’s quantitative screening system, which evaluates stocks based on earnings consistency, capital efficiency, financial safety, valuation discipline, and price trend.

At the time of this review, Cellectis trades at $0.98 per share. The StockValueFinder system assigned CLLS a score of 33%, resulting in an "AVOID" rating. This score reflects a combination of weak financial metrics, negative profitability trends, and an unfavorable price trend signal. Below, we break down each key metric to help readers understand how the system evaluates stocks and why CLLS received this rating.

Why the StockValueFinder Score Matters

The StockValueFinder score is a composite measure designed to help investors identify stocks that meet a set of quantitative financial and valuation criteria. The score ranges from 0% to 100%, with higher scores indicating stronger alignment with the system’s preferred metrics. A score of 33% for CLLS suggests that the stock falls below the threshold for what the system considers a high-quality investment candidate.

Scores are not predictions of future performance. Instead, they reflect how well a company’s current financial health and valuation align with historically favorable ranges for long-term investing. In this review, we will explore each metric in detail to explain why CLLS scored as it did.

EPS Strength and Consistency

**Metric Result:** Did not pass

Earnings per share (EPS) is a fundamental measure of a company’s profitability. It represents the portion of a company’s profit allocated to each outstanding share of common stock. Consistency in EPS growth is often associated with stable business models and disciplined financial management.

StockValueFinder’s EPS test evaluates whether a company has demonstrated a history of positive and growing earnings. While the exact EPS values for CLLS are not supplied, the system recorded a "Did not pass" result, indicating that the company has not met the criteria for consistent profitability.

**Why EPS Consistency Matters:** - Companies with stable or growing EPS are generally better positioned to reinvest in their operations, pay dividends, or reduce debt. - Inconsistent or negative EPS may signal operational challenges, competitive pressures, or high research and development costs, which are common in the biotechnology sector. - For example, a company with EPS of $1.20, $1.35, and $1.50 over three consecutive years demonstrates steady growth. In contrast, a company with EPS of -$0.50, $0.10, and -$0.30 shows volatility and potential financial instability.

For CLLS, the failure to pass the EPS test suggests that the company has not yet achieved consistent profitability, a common characteristic of early-stage biotechnology firms that are still investing heavily in research and clinical trials.

ROIC and Capital Efficiency

**Metric Result:** -34.52% (Did not pass)

Return on invested capital (ROIC) measures how effectively a company uses its capital to generate profits. It is calculated as net operating profit after taxes (NOPAT) divided by invested capital. ROIC is a critical metric for assessing a company’s efficiency in deploying capital, whether for research, acquisitions, or operational expansion.

StockValueFinder generally prefers companies with an ROIC of 10% or higher. This threshold indicates that the company is generating sufficient returns to justify the capital invested in its operations.

**CLLS ROIC Analysis:** - CLLS has an ROIC of -34.52%, which is significantly below the preferred 10% threshold. - A negative ROIC suggests that the company is not generating enough profit to cover its cost of capital. In other words, the company is losing money on its investments. - For context, a company with an ROIC of 15% is typically using its capital more efficiently than one with an ROIC of 4%. The former is generating $15 in profit for every $100 invested, while the latter generates only $4.

**Why ROIC Matters for CLLS:** - Biotechnology companies often have negative ROIC in their early stages due to high research and development (R&D) costs and the long timeline for commercializing products. - However, a sustained negative ROIC may indicate that the company’s business model is not yet viable or that its R&D investments are not yielding sufficient returns. - Investors should monitor whether CLLS can transition to positive ROIC as its therapies progress through clinical trials and potentially reach commercialization.

Interest Coverage and Financial Safety

**Metric Result:** Did not pass

Interest coverage is a measure of a company’s ability to meet its interest payments on outstanding debt. It is calculated as earnings before interest and taxes (EBIT) divided by interest expense. A higher interest coverage ratio indicates greater financial flexibility and lower risk of default.

StockValueFinder prefers companies with an interest coverage ratio of 6 or higher. This threshold suggests that the company generates enough operating income to comfortably cover its interest obligations.

**CLLS Interest Coverage Analysis:** - The system recorded a "Did not pass" result for CLLS, indicating that the company’s interest coverage ratio is below the preferred threshold of 6. - While the exact interest coverage ratio for CLLS is not supplied, the failure to pass this test suggests that the company may be struggling to generate sufficient earnings to cover its debt obligations. - For example, a company with an interest coverage ratio of 8x is in a stronger financial position than one with a ratio of 2x. The former generates $8 in operating income for every $1 of interest expense, while the latter generates only $2.

**Why Interest Coverage Matters for CLLS:** - Low or negative interest coverage can signal financial distress, particularly for companies with high debt levels. - Biotechnology companies often rely on debt or equity financing to fund R&D, which can lead to high interest expenses if profitability is not yet achieved. - Investors should assess whether CLLS has sufficient cash reserves or access to additional funding to meet its debt obligations while continuing its operations.

Debt Payback and Balance Sheet Discipline

**Metric Result:** -1.21 years (Passed)

Debt payback measures how long it would take a company to pay off its total debt using its current operating income. It is calculated as total debt divided by operating income. A shorter debt payback period indicates a stronger balance sheet and lower financial risk.

StockValueFinder prefers companies with a debt payback period of 3 years or less. This threshold suggests that the company can quickly eliminate its debt burden if needed.

**CLLS Debt Payback Analysis:** - CLLS has a debt payback period of -1.21 years, which is below the preferred threshold of 3 years. - The negative value indicates that the company is not generating positive operating income, making it impossible to calculate a traditional debt payback period. - Despite the negative value, the system recorded a "Passed" result for this test. This may reflect the system’s recognition that biotechnology companies often operate with negative operating income during their development phases.

**Why Debt Payback Matters for CLLS:** - While the negative debt payback period is not ideal, it is not uncommon for early-stage biotechnology companies. - Investors should monitor whether CLLS can transition to positive operating income as its therapies advance through clinical trials. - A company with a debt payback period of 1.5 years is generally in a stronger financial position than one with a period of 7 years, as the former can eliminate its debt more quickly.

P/E Ratio and Valuation Discipline

**Metric Result:** -1.60 (Passed)

The price-to-earnings (P/E) ratio is a valuation metric that compares a company’s stock price to its earnings per share. It is calculated as the stock price divided by EPS. A lower P/E ratio may indicate that a stock is undervalued, while a higher P/E ratio may suggest overvaluation.

StockValueFinder prefers companies with a P/E ratio of 15 or lower. This threshold is designed to identify stocks that are trading at reasonable valuations relative to their earnings.

**CLLS P/E Ratio Analysis:** - CLLS has a P/E ratio of -1.60, which is below the preferred threshold of 15. - The negative P/E ratio reflects the company’s negative earnings, meaning it is not currently profitable. - Despite the negative value, the system recorded a "Passed" result for this test. This may reflect the system’s recognition that biotechnology companies often trade at negative P/E ratios during their development phases.

**Why P/E Ratio Matters for CLLS:** - A negative P/E ratio is not meaningful in the traditional sense, as it does not provide insight into the company’s valuation relative to its earnings. - For example, a company with a P/E ratio of 8 is generally considered more attractively valued than one with a P/E ratio of 40, assuming both companies have similar growth prospects and business quality. - Investors should focus on other metrics, such as cash reserves and clinical trial progress, to assess CLLS’s potential value.

Moving Average Trend and Entry Timing

**Metric Result:** SELL / AVOID TREND (Entry Signal: N/A)

Moving averages are technical indicators used to smooth out price data and identify trends. StockValueFinder uses moving averages to assess the overall price trend of a stock, which can help investors avoid entering positions during unfavorable market conditions.

**CLLS Moving Average Analysis:** - The system recorded a "SELL / AVOID TREND" signal for CLLS, indicating that the stock’s price trend is unfavorable. - The entry signal is marked as "N/A," meaning the system does not identify a favorable entry point at this time. - Moving averages are not predictive tools but rather reflect the stock’s recent price action. For example, if a stock’s price is consistently below its 200-day moving average, it may indicate a downtrend.

**Why Moving Average Trends Matter for CLLS:** - A "SELL / AVOID TREND" signal suggests that the stock’s price has been declining or trading below key moving averages. - Investors should be cautious about entering positions in stocks with unfavorable trends, as they may face additional downside risk. - It is important to note that moving averages are not guarantees of future performance but rather tools for assessing the current market environment.

Overall Financial Strengths and Weaknesses

**Strengths:** - **Debt Payback Test Passed:** While the debt payback period is negative, the system still recorded a "Passed" result, which may reflect the unique financial dynamics of early-stage biotechnology companies. - **P/E Valuation Test Passed:** The negative P/E ratio is not ideal, but the system’s "Passed" result acknowledges the challenges of valuing development-stage companies.

**Weaknesses:** - **EPS Test Failed:** The company has not demonstrated consistent profitability, a common issue for biotechnology firms in their early stages. - **ROIC Test Failed:** The negative ROIC of -34.52% indicates that the company is not generating sufficient returns on its invested capital. - **Interest Coverage Test Failed:** The company’s ability to cover its interest obligations is likely weak, signaling potential financial risk. - **Unfavorable Price Trend:** The "SELL / AVOID TREND" signal suggests that the stock’s price action is unfavorable, which may deter investors looking for positive momentum.

Risks and Limitations

Investing in Cellectis SA (CLLS) carries several risks and limitations that investors should consider:

1. **Clinical and Regulatory Risk:** As a clinical-stage biotechnology company, CLLS’s success depends on the outcome of its clinical trials and regulatory approvals. Failure to achieve positive trial results or secure regulatory clearance could significantly impact the company’s financial health and stock price.

2. **Financial Risk:** CLLS’s negative profitability, negative ROIC, and weak interest coverage ratio indicate financial instability. The company may need to raise additional capital through debt or equity offerings, which could dilute existing shareholders or increase financial leverage.

3. **Market Risk:** The biotechnology sector is highly competitive and subject to rapid technological advancements. CLLS must compete with larger, more established companies that have greater resources and commercialization capabilities.

4. **Liquidity Risk:** CLLS’s low stock price and potentially low trading volume may result in higher bid-ask spreads and increased volatility, making it difficult to enter or exit positions at desired prices.

5. **Valuation Risk:** The negative P/E ratio and lack of consistent earnings make it challenging to assess the company’s intrinsic value. Investors must rely on other metrics, such as cash reserves and clinical trial progress, to evaluate the stock.

Educational Conclusion

This review of Cellectis SA (CLLS) provides an educational breakdown of how StockValueFinder’s quantitative screening system evaluates stocks. The system’s "AVOID" rating and 33% score reflect a combination of weak financial metrics, negative profitability trends, and an unfavorable price trend.

Key takeaways for investors include

**EPS Consistency:** CLLS has not demonstrated consistent profitability, a common challenge for early-stage biotechnology companies. - **ROIC:** The company’s negative ROIC of -34.52% indicates inefficiency in generating returns on invested capital. - **Interest Coverage:** The failure to pass the interest coverage test suggests potential financial risk, particularly if the company carries significant debt. - **Debt Payback:** While the system recorded a "Passed" result for debt payback, the negative value highlights the company’s lack of positive operating income. - **P/E Ratio:** The negative P/E ratio of -1.60 is not meaningful in the traditional sense but reflects the company’s current lack of profitability. - **Price Trend:** The "SELL / AVOID TREND" signal indicates an unfavorable price trend, which may deter momentum-focused investors.

Investors should use this review as a starting point for further research. It is essential to consider the unique risks and dynamics of the biotechnology sector, as well as the company’s clinical trial progress and financial flexibility. StockValueFinder’s metrics are designed to provide a disciplined framework for evaluating stocks, but they are not guarantees of future performance.

This article is for research and educational purposes only. It is not personal financial advice, investment advice, or a recommendation to buy or sell any security.


Research links: Yahoo Finance | Seeking Alpha | Finviz | SEC Filings

Research Attribution
Gabe L. Michaels

Financial Markets Commentator. Known for his direct approach to financial markets and his skepticism toward conventional Wall Street narratives, Michaels focuses on the economic forces that influence investment performance, dividend sustainability, and long-term wealth preservation. His commentary emphasizes the importance of understanding monetary policy, inflation, government debt, interest rates, and the risks associated with speculative investing.

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