ETF Research

IDNA: ISHARES GENOMICS IMMUNOLOGY AND HEALTHCARE ETF

Generated from StockValueFinder data · Updated Oct 11, 2026 10:12 PM
Educational content only. This is not financial advice and is not a recommendation to buy, sell, or hold any ETF.

ETF Education Report: ISHARES GENOMICS IMMUNOLOGY AND HEALTHCARE ETF (IDNA)

What this ETF is trying to do

The ISHARES GENOMICS IMMUNOLOGY AND HEALTHCARE ETF (ticker: IDNA) is an exchange-traded fund that focuses on the healthcare sector. Specifically, it targets companies involved in genomics, immunology, and general healthcare.

Top Holdings

The following are the largest companies held by this ETF (note that this is a partial list):

• Moderna Inc (11.20%)

• Twist Bioscience Corp (7.70%)

• Iovance Biotherapeutics Inc (4.98%)

• Genmab AS (3.98%)

• Revolution Medicines Inc (3.79%)

• Bayer AG (3.60%)

• Merck & Co Inc (3.32%)

• Takeda Pharmaceutical Co Ltd (3.30%)

• Regeneron Pharmaceuticals Inc (3.29%)

• Incyte Corp (3.27%)

What the numbers show

When looking at ETF performance, it is important to distinguish between price return (how much the share price changed) and total return (which includes the impact of distributions).

• Year-to-Date (YTD): The price return is approximately 56.05%, while the total return is approximately 56.71%.

• One-Year: The price return was approximately 66.54%, and the total return was approximately 68.24%.

• Three-Year: The price return was approximately 106.41%, and the total return was approximately 113.65%.

For context, the estimated price from roughly one year ago was $24.54. The current price is $40.87.

Income and distribution explanation

This ETF provides some cash income through distributions. The distribution yield is approximately 0.69%. Over the last 12 months, there were 2 payouts. The distribution frequency is described as irregular or less frequent. It is important to remember that a distribution yield shows the cash paid out relative to the price, but it is not the same as the total return.

NAV erosion explanation

"NAV erosion" refers to a decline in the Net Asset Value (the actual value of the assets held by the fund). Some investors worry about erosion because it can mean the fund is losing value over time. For IDNA, the erosion-risk score is 100, and the label indicates "No price erosion detected." There is no severe erosion-risk flag for this ETF.

Pros

• The ETF has shown strong positive price returns over the one-year and three-year periods.

• The total return figures are higher than the price return figures, meaning distributions added to the overall value.

• The erosion-risk measurement is rated as "good."

Cons

• The five-year total return was approximately -9.71%.

• The distribution yield is relatively low at 0.69%.

• Distributions are irregular rather than occurring on a steady monthly or quarterly schedule.

Beginner takeaway

IDNA focuses on specialized healthcare companies like Moderna and Twist Bioscience. While it has seen significant price growth recently, long-term data (five years) shows a negative total return. Investors should always look at both price returns and total returns to see the full picture of how an ETF has performed.

Top Holdings

Structured portfolio holdings supplied by the ETF data provider. These figures are not generated by the AI article.

66 holdings available
# Holding Ticker Weight
1 MODERNA INC MRNA 11.20%
2 TWIST BIOSCIENCE CORP TWST 7.70%
3 IOVANCE BIOTHERAPEUTICS INC IOVA 4.98%
4 GENMAB AS n/a 3.98%
5 REVOLUTION MEDICINES INC ORDINARY SHARES RVMD 3.79%
6 BAYER AG n/a 3.60%
7 MERCK & CO INC MRK 3.32%
8 TAKEDA PHARMACEUTICAL CO LTD n/a 3.30%
9 REGENERON PHARMACEUTICALS INC REGN 3.29%
10 INCYTE CORP INCY 3.27%
Show all 66 holdings
1. MODERNA INC MRNA 11.20%
2. TWIST BIOSCIENCE CORP TWST 7.70%
3. IOVANCE BIOTHERAPEUTICS INC IOVA 4.98%
4. GENMAB AS n/a 3.98%
5. REVOLUTION MEDICINES INC ORDINARY SHARES RVMD 3.79%
6. BAYER AG n/a 3.60%
7. MERCK & CO INC MRK 3.32%
8. TAKEDA PHARMACEUTICAL CO LTD n/a 3.30%
9. REGENERON PHARMACEUTICALS INC REGN 3.29%
10. INCYTE CORP INCY 3.27%
11. CARIS LIFE SCIENCES INC CAI 3.25%
12. VERTEX PHARMACEUTICALS INC VRTX 3.23%
13. BIONTECH SE ADR BNTX 3.08%
14. IMMUNITYBIO INC ORDINARY SHARES IBRX 3.08%
15. EXELIXIS INC EXEL 3.06%
16. ABCELLERA BIOLOGICS INC ORDINARY SHARES ABCL 2.96%
17. ROCHE HOLDING AG ORDINARY SHARES NEW n/a 2.80%
18. IDEAYA BIOSCIENCES INC IDYA 2.77%
19. GSK PLC n/a 2.59%
20. SANOFI SA n/a 2.53%
21. IPSEN SA n/a 2.44%
22. ARCUS BIOSCIENCES INC RCUS 1.87%
23. NOVAVAX INC NVAX 1.46%
24. ONO PHARMACEUTICAL CO LTD n/a 1.45%
25. CRISPR THERAPEUTICS AG CRSP 1.37%
26. VIR BIOTECHNOLOGY INC VIR 1.29%
27. n/a NUVB 1.20%
28. PERSONALIS INC PSNL 0.87%
29. JANUX THERAPEUTICS INC ORDINARY SHARES JANX 0.86%
30. KURA ONCOLOGY INC KURA 0.80%
31. n/a n/a 0.76%
32. RIGEL PHARMACEUTICALS INC RIGL 0.75%
33. n/a n/a 0.70%
34. CORVUS PHARMACEUTICALS INC CRVS 0.63%
35. PACIFIC BIOSCIENCES OF CALIFORNIA INC PACB 0.59%
36. ALVOTECH ALVO 0.57%
37. VERASTEM INC VSTM 0.57%
38. GINKGO BIOWORKS HOLDINGS INC DNA 0.52%
39. XENCOR INC XNCR 0.48%
40. INTELLIA THERAPEUTICS INC NTLA 0.44%
41. VALNEVA SE n/a 0.43%
42. CYTOMX THERAPEUTICS INC CTMX 0.41%
43. DESIGN THERAPEUTICS INC DSGN 0.41%
44. SHANGHAI HENLIUS BIOTECH INC CLASS H n/a 0.40%
45. OCUGEN INC OCGN 0.30%
46. ABCLON INC n/a 0.23%
47. BLACKROCK CASH FUNDS TREASURY SL AGENCY n/a 0.11%
48. JPY CASH n/a 0.09%
49. PRIME MEDICINE INC PRME 0.08%
50. USD CASH n/a 0.06%
51. GBP CASH n/a 0.04%
52. JPY/USD PURCHASED n/a 0.02%
53. CHF CASH n/a 0.01%
54. ARCELLX INC CVR n/a 0.00%
55. CASH OFFSET n/a 0.00%
56. DKK CASH n/a 0.00%
57. E-MINI HEALTH CARE SECTOR DEC 26 n/a 0.00%
58. EUR CASH n/a 0.00%
59. HKD CASH n/a 0.00%
60. KRW/USD PURCHASED n/a 0.00%
61. KRW/USD SOLD n/a 0.00%
62. OMNIAB INC $12.50 VESTING PRVT n/a 0.00%
63. OMNIAB INC $15.00 VESTING PRVT n/a 0.00%
64. TWD CASH n/a 0.00%
65. KRW CASH n/a 0.00%
66. JPY/USD SOLD n/a 0.00%
Holdings data last updated Oct 7, 2026 6:25 AM .
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