ETF Research

IBRN: ISHARES NEUROSCIENCE AND HEALTHCARE ETF

Generated from StockValueFinder data · Updated Oct 11, 2026 10:13 PM
Educational content only. This is not financial advice and is not a recommendation to buy, sell, or hold any ETF.

ETF Education Report: iShares Neuroscience and Healthcare ETF (IBRN)

What this ETF is trying to do

The iShares Neuroscience and Healthcare ETF (IBRN) focuses on companies involved in neuroscience and healthcare. It holds a variety of different stocks within this specific medical field. According to the data, the fund holds 94 total companies.

What the numbers show

When looking at how this ETF has performed, it is important to look at two different types of returns: price return and total return. Price return only tracks how the share price changes. Total return includes both the price change and any cash distributions (dividends) paid out.

• Year-to-Date (YTD): The YTD price return is approximately -0.86%. The YTD total return is also approximately -0.86%.

• One Year: The one-year price return was approximately 15.34%. However, the one-year total return was higher at approximately 16.49%.

• Three Years: The three-year price return was approximately 51.42%. The three-year total return was approximately 53.56%.

To give you an idea of the price movement, the current price is $32.04. The estimated price from roughly one year ago was approximately $27.78.

Income and distribution explanation

This ETF provides some cash income through distributions. The distribution yield is approximately 0.99%. This number describes the cash paid out relative to the ETF's price. It is important to remember that a distribution yield is not the same as total return.

The data shows the distributions are "irregular," meaning they do not happen on a set schedule. In the last 12 months, there was one payout.

NAV erosion explanation

"NAV erosion" is a term used to describe when the value of the underlying assets in a fund decreases significantly over time. Some investors worry about this because they want their original investment to stay stable.

For IBRN, the erosion-risk score is 100, and the label states "No price erosion detected." The erosion severity is rated as "good," and there is no severe erosion-risk flag.

Top Holdings

The following are the top holdings in this ETF. Please note that this is a partial list of the largest companies held:

• Edwise Therapeutics Inc (4.47%)

• Biogen Inc (4.42%)

• PTC Therapeutics Inc (4.12%)

• Acadia Pharmaceuticals Inc (4.08%)

• Alkermes PLC (4.06%)

• Argenx SE ADR (4.04%)

• Scholar Rock Holding Corp (4.00%)

• Neurocrine Biosciences Inc (3.96%)

• Diantus Therapeutics Inc (3.93%)

• Prax (3.69%)

Pros

• The ETF has shown positive price and total returns over the one-year and three-year periods.

• The erosion-risk measurements suggest no significant price erosion has been detected.

Cons

• The year-to-date (YTD) performance has been slightly negative.

• Distributions are irregular and less frequent.

Beginner takeaway

When studying an ETF like IBRN, always look at the difference between price return and total return. Total return gives a fuller picture because it includes the cash paid out to investors. Also, while this fund pays a distribution yield, high yields alone do not tell the whole story of how an investment is performing.

Top Holdings

Structured portfolio holdings supplied by the ETF data provider. These figures are not generated by the AI article.

94 holdings available
# Holding Ticker Weight
1 EDGEWISE THERAPEUTICS INC EWTX 4.47%
2 BIOGEN INC BIIB 4.42%
3 PTC THERAPEUTICS INC PTCT 4.12%
4 ACADIA PHARMACEUTICALS INC ACAD 4.08%
5 ALKERMES PLC ALKS 4.06%
6 ARGENX SE ADR ARGX 4.04%
7 SCHOLAR ROCK HOLDING CORP SRRK 4.00%
8 NEUROCRINE BIOSCIENCES INC NBIX 3.96%
9 DIANTHUS THERAPEUTICS INC DNTH 3.93%
10 n/a PRAX 3.69%
Show all 94 holdings
1. EDGEWISE THERAPEUTICS INC EWTX 4.47%
2. BIOGEN INC BIIB 4.42%
3. PTC THERAPEUTICS INC PTCT 4.12%
4. ACADIA PHARMACEUTICALS INC ACAD 4.08%
5. ALKERMES PLC ALKS 4.06%
6. ARGENX SE ADR ARGX 4.04%
7. SCHOLAR ROCK HOLDING CORP SRRK 4.00%
8. NEUROCRINE BIOSCIENCES INC NBIX 3.96%
9. DIANTHUS THERAPEUTICS INC DNTH 3.93%
10. n/a PRAX 3.69%
11. SUPERNUS PHARMACEUTICALS INC SUPN 3.25%
12. AXOGEN INC AXGN 3.20%
13. DYNE THERAPEUTICS INC ORDINARY SHARES DYN 3.05%
14. n/a n/a 3.03%
15. SAREPTA THERAPEUTICS INC SRPT 2.87%
16. XENON PHARMACEUTICALS INC XENE 2.83%
17. BIOHAVEN LTD BHVN 2.60%
18. H. LUNDBECK AS ORDINARY SHARES CLASS B n/a 2.49%
19. NEUREN PHARMACEUTICALS LTD n/a 2.23%
20. BIOARCTIC AB CLASS B n/a 1.94%
21. n/a TSHA 1.86%
22. RAPPORT THERAPEUTICS INC RAPP 1.62%
23. ONCOLYS BIOPHARMA INC n/a 1.57%
24. LB PHARMACEUTICALS INC LBRX 1.54%
25. ALTO NEUROSCIENCE INC ANRO 1.49%
26. IDORSIA LTD n/a 1.48%
27. INTEGRA LIFESCIENCES HOLDINGS CORP IART 1.47%
28. APNIMED INC APMD 1.35%
29. RUBICON RESEARCH LTD n/a 1.23%
30. DYNAVOX GROUP AB n/a 1.06%
31. SOLID BIOSCIENCES INC SLDB 1.04%
32. ANNEXON INC ORDINARY SHARES ANNX 0.93%
33. CERIBELL INC CBLL 0.85%
34. MEDINCELL SA n/a 0.84%
35. METIS TECHBIO CO LTD CLASS H n/a 0.74%
36. NEUROGENE INC NGNE 0.72%
37. BRAINSWAY LTD ADR BWAY 0.68%
38. CAPRICOR THERAPEUTICS INC CAPR 0.68%
39. OVID THERAPEUTICS INC OVID 0.68%
40. n/a DRUG 0.63%
41. DESIGN THERAPEUTICS INC DSGN 0.61%
42. CLEARPOINT NEURO INC CLPT 0.59%
43. PROTHENA CORP PLC PRTA 0.56%
44. NEUROPACE INC NPCE 0.55%
45. BENITEC BIOPHARMA INC BNTC 0.51%
46. n/a n/a 0.49%
47. SANBIO CO LTD n/a 0.49%
48. JPY/USD PURCHASED n/a 0.45%
49. ABEONA THERAPEUTICS INC ABEO 0.41%
50. VANDA PHARMACEUTICALS INC VNDA 0.41%
51. KYVERNA THERAPEUTICS INC KYTX 0.40%
52. MICROPORT NEUROSCIENTIFIC CORP n/a 0.36%
53. SANTHERA PHARMACEUTICALS HOLDING AG n/a 0.35%
54. NEWRON PHARMACEUTICALS SPA n/a 0.33%
55. ANAVEX LIFE SCIENCES CORP AVXL 0.31%
56. BLACKROCK CASH FUNDS TREASURY SL AGENCY n/a 0.29%
57. LARIMAR THERAPEUTICS INC LRMR 0.25%
58. PEPGEN INC PEPG 0.25%
59. TONIX PHARMACEUTICALS HOLDING CORP TNXP 0.25%
60. NERVGEN PHARMA CORP ORDINARY SHARES NGEN 0.24%
61. ACUMEN PHARMACEUTICALS INC ABOS 0.23%
62. ALECTOR INC ALEC 0.23%
63. ENTRADA THERAPEUTICS INC TRDA 0.22%
64. VOYAGER THERAPEUTICS INC VYGR 0.22%
65. CAMP4 THERAPEUTICS CORP CAMP 0.20%
66. MINERVA NEUROSCIENCES INC NERV 0.18%
67. MAPLIGHT THERAPEUTICS INC MPLT 0.17%
68. MOBIA MEDICAL INC MOBI 0.17%
69. COGNITION THERAPEUTICS INC CGTX 0.12%
70. NEUMORA THERAPEUTICS INC NMRA 0.08%
71. CHF CASH n/a 0.05%
72. SEK CASH n/a 0.05%
73. SEK/USD PURCHASED n/a 0.05%
74. AUD CASH n/a 0.04%
75. CHF/USD PURCHASED n/a 0.04%
76. DKK CASH n/a 0.04%
77. KRW CASH n/a 0.04%
78. KRW/USD PURCHASED n/a 0.03%
79. DKK/USD PURCHASED n/a 0.02%
80. EUR CASH n/a 0.02%
81. AUD/USD PURCHASED n/a 0.01%
82. EUR/USD PURCHASED n/a 0.01%
83. HKD CASH n/a 0.01%
84. CASH OFFSET n/a 0.00%
85. MICRO E-MINI RUSSELL 2000 DEC 26 n/a 0.00%
86. AUD/USD SOLD n/a 0.00%
87. EUR/USD SOLD n/a 0.00%
88. USD CASH n/a 0.00%
89. DKK/USD SOLD n/a 0.00%
90. KRW/USD SOLD n/a 0.00%
91. CHF/USD SOLD n/a 0.00%
92. SEK/USD SOLD n/a 0.00%
93. JPY CASH n/a 0.00%
94. JPY/USD SOLD n/a 0.00%
Holdings data last updated Oct 7, 2026 6:25 AM . Provider-reported weights may not sum exactly to 100%.
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