ETF Research

IBB: ISHARES BIOTECHNOLOGY ETF

Generated from StockValueFinder data · Updated Oct 13, 2026 9:49 AM
Educational content only. This is not financial advice and is not a recommendation to buy, sell, or hold any ETF.

Share-split context: A forward split was recorded on Dec 1, 2017 with coefficient 3. A forward split turns each old share into multiple new shares and lowers the quoted price per share proportionally. Proportional ownership is unchanged at the split moment, so the split itself creates neither a gain nor a loss. The price-return figures in this report are already split-adjusted.

Understanding the iShares Biotechnology ETF (IBB)

The iShares Biotechnology ETF (ticker: IBB) is designed to give investors exposure to the biotechnology sector. This ETF holds a variety of companies involved in biotech research and development.

What this ETF is trying to do

IBB tracks the biotechnology industry by investing in many different companies. Instead of buying just one stock, this ETF allows you to own a small piece of many different biotech firms at once. According to the provided data, the fund holds 251 total holdings.

Top Holdings:

The following are some of the largest companies in the fund (note that this is a partial list):

• AMGEN INC (8.45%)

• VERTEX PHARMACEUTICALS INC (8.06%)

• GILEAD SCIENCES INC (7.21%)

• REGENERON PHARMACEUTICALS INC (5.72%)

• ARGENX SE ADR (3.80%)

• MODERNA INC (3.62%)

• NATERA INC (3.12%)

• REVOLUTION MEDICINES INC (2.78%)

• ILLUMINA INC (2.29%)

• ALNYLAM PHARMACEUTICALS INC (2.27%)

*Please note: Holdings can change over time.*

What the numbers show

The performance of IBB is shown through two different types of returns: price return (the change in the share price) and total return (which includes the impact of distributions).

• Year-to-Date (YTD): The price return is approximately 20.48%, while the total return is approximately 20.59%.

• One-Year: The price return was approximately 35.13%, and the total return was approximately 35.40%.

• Three-Year: The price return was approximately 66.02%, and the total return was approximately 67.22%.

IBB has a history of "forward splits." This means that in the past, each old share became multiple new shares. When this happens, the price per share falls proportionally, but your total ownership stays the same. This is a normal structural event and not a loss of value.

Income and distribution explanation

IBB provides some income through distributions. The current distribution yield is approximately 0.17%. This represents the cash paid out relative to the ETF's price. The fund usually pays these distributions quarterly, with 4 payments recorded over the last 12 months.

It is important to remember that a distribution yield is not the same as total return. While distributions provide cash, they are separate from the growth of the share price itself.

NAV erosion explanation

"NAV erosion" refers to a decline in the Net Asset Value (the actual value of the assets held by the fund). The supplied data is sufficient to evaluate price erosion, but it does not include enough historical NAV-per-share data to confirm or rule out NAV erosion.

However, regarding the market price, the erosion-risk score is 100, which is labeled as "No price erosion detected." The erosion severity is rated as "good," and there is no severe erosion-risk flag.

Pros

• Strong Price Growth: The fund has shown significant positive price returns over the one-year and three-year periods.

• Diversification: It provides exposure to a large number of companies (251 total) within the biotech sector.

Cons

• Low Yield: The distribution yield is quite low (0.17%), meaning it is not primarily designed to be a high-income investment.

Beginner takeaway

IBB is an ETF focused on the biotechnology industry. It has recently shown strong price growth and total returns. While it does pay small distributions, its main characteristic is its exposure to biotech stocks rather than high cash income.

Top Holdings

Structured portfolio holdings supplied by the ETF data provider. These figures are not generated by the AI article.

251 holdings available
# Holding Ticker Weight
1 AMGEN INC AMGN 8.45%
2 VERTEX PHARMACEUTICALS INC VRTX 8.06%
3 GILEAD SCIENCES INC GILD 7.21%
4 REGENERON PHARMACEUTICALS INC REGN 5.72%
5 ARGENX SE ADR ARGX 3.80%
6 MODERNA INC MRNA 3.62%
7 NATERA INC NTRA 3.12%
8 REVOLUTION MEDICINES INC ORDINARY SHARES RVMD 2.78%
9 ILLUMINA INC ILMN 2.29%
10 ALNYLAM PHARMACEUTICALS INC ALNY 2.27%
Show all 251 holdings
1. AMGEN INC AMGN 8.45%
2. VERTEX PHARMACEUTICALS INC VRTX 8.06%
3. GILEAD SCIENCES INC GILD 7.21%
4. REGENERON PHARMACEUTICALS INC REGN 5.72%
5. ARGENX SE ADR ARGX 3.80%
6. MODERNA INC MRNA 3.62%
7. NATERA INC NTRA 3.12%
8. REVOLUTION MEDICINES INC ORDINARY SHARES RVMD 2.78%
9. ILLUMINA INC ILMN 2.29%
10. ALNYLAM PHARMACEUTICALS INC ALNY 2.27%
11. BIOGEN INC BIIB 2.25%
12. BEONE MEDICINES LTD ADR ONC 2.03%
13. INSMED INC INSM 1.85%
14. INCYTE CORP INCY 1.73%
15. UNITED THERAPEUTICS CORP UTHR 1.49%
16. ROIVANT SCIENCES LTD ORDINARY SHARES ROIV 1.27%
17. GENMAB AS ADR GMAB 1.23%
18. ASCENDIS PHARMA AS ASND 1.15%
19. NEUROCRINE BIOSCIENCES INC NBIX 1.08%
20. MEDPACE HOLDINGS INC MEDP 0.97%
21. n/a CRL 0.97%
22. EXELIXIS INC EXEL 0.94%
23. BRIDGEBIO PHARMA INC BBIO 0.92%
24. HALOZYME THERAPEUTICS INC HALO 0.89%
25. BIOMARIN PHARMACEUTICAL INC BMRN 0.88%
26. MADRIGAL PHARMACEUTICALS INC MDGL 0.83%
27. BIO-TECHNE CORP TECH 0.80%
28. ARROWHEAD PHARMACEUTICALS INC ARWR 0.77%
29. IONIS PHARMACEUTICALS INC IONS 0.69%
30. REPLIGEN CORP RGEN 0.68%
31. CYTOKINETICS INC CYTK 0.67%
32. BIONTECH SE ADR BNTX 0.66%
33. KRYSTAL BIOTECH INC KRYS 0.66%
34. n/a PRAX 0.65%
35. PROTAGONIST THERAPEUTICS INC PTGX 0.64%
36. AXSOME THERAPEUTICS INC AXSM 0.61%
37. VAXCYTE INC ORDINARY SHARES PCVX 0.61%
38. KYMERA THERAPEUTICS INC ORDINARY SHARES KYMR 0.60%
39. CRINETICS PHARMACEUTICALS INC n/a 0.59%
40. TWIST BIOSCIENCE CORP TWST 0.59%
41. APOGEE THERAPEUTICS INC n/a 0.55%
42. ALKERMES PLC ALKS 0.54%
43. ABIVAX SA ADR ABVX 0.51%
44. n/a TXG 0.50%
45. RHYTHM PHARMACEUTICALS INC RYTM 0.50%
46. SPYRE THERAPEUTICS INC SYRE 0.49%
47. TEMPUS AI INC CLASS A COMMON STOCK TEM 0.47%
48. BRUKER CORP BRKR 0.46%
49. TRAVERE THERAPEUTICS INC ORDINARY SHARES TVTX 0.42%
50. PTC THERAPEUTICS INC PTCT 0.39%
51. SCHOLAR ROCK HOLDING CORP SRRK 0.39%
52. XENON PHARMACEUTICALS INC XENE 0.39%
53. COGENT BIOSCIENCES INC COGT 0.36%
54. CRISPR THERAPEUTICS AG CRSP 0.36%
55. n/a DFTX 0.36%
56. ACADIA PHARMACEUTICALS INC ACAD 0.35%
57. MIRUM PHARMACEUTICALS INC MIRM 0.35%
58. ORUKA THERAPEUTICS INC ORKA 0.33%
59. CG ONCOLOGY INC CGON 0.31%
60. ERASCA INC ERAS 0.31%
61. ADAPTIVE BIOTECHNOLOGIES CORP ADPT 0.27%
62. DYNE THERAPEUTICS INC ORDINARY SHARES DYN 0.27%
63. AMYLYX PHARMACEUTICALS INC AMLX 0.25%
64. DENALI THERAPEUTICS INC DNLI 0.25%
65. IDEAYA BIOSCIENCES INC IDYA 0.24%
66. VERACYTE INC VCYT 0.24%
67. EDGEWISE THERAPEUTICS INC EWTX 0.23%
68. ENLIVEN THERAPEUTICS INC ELVN 0.23%
69. IMMUNOVANT INC IMVT 0.23%
70. CARIS LIFE SCIENCES INC CAI 0.22%
71. GRAIL INC GRAL 0.22%
72. IOVANCE BIOTHERAPEUTICS INC IOVA 0.22%
73. LEGEND BIOTECH CORP ADR LEGN 0.22%
74. UNIQURE NV QURE 0.22%
75. IMMUNITYBIO INC ORDINARY SHARES IBRX 0.21%
76. n/a TARS 0.21%
77. RELAY THERAPEUTICS INC ORDINARY SHARES RLAY 0.21%
78. BEAM THERAPEUTICS INC BEAM 0.20%
79. ABCELLERA BIOLOGICS INC ORDINARY SHARES ABCL 0.19%
80. n/a ARQT 0.19%
81. STRUCTURE THERAPEUTICS INC ADR GPCR 0.19%
82. TANGO THERAPEUTICS INC TNGX 0.19%
83. NURIX THERAPEUTICS INC ORDINARY SHARES NRIX 0.18%
84. ARCUS BIOSCIENCES INC RCUS 0.17%
85. CAREDX INC CDNA 0.17%
86. ULTRAGENYX PHARMACEUTICAL INC RARE 0.16%
87. ZAI LAB LTD ADR REPR 1 SHS ZLAB 0.16%
88. ADMA BIOLOGICS INC ADMA 0.15%
89. ATAIBECKLEY INC ATAI 0.15%
90. BIOCRYST PHARMACEUTICALS INC BCRX 0.15%
91. DISC MEDICINE INC ORDINARY SHARES IRON 0.15%
92. KODIAK SCIENCES INC KOD 0.15%
93. SAREPTA THERAPEUTICS INC SRPT 0.15%
94. ZYMEWORKS INC REGISTERED SHS ZYME 0.15%
95. BIOHAVEN LTD BHVN 0.14%
96. NEWAMSTERDAM PHARMA CO NV NAMS 0.14%
97. VERA THERAPEUTICS INC CLASS A VERA 0.14%
98. VERICEL CORP VCEL 0.14%
99. AGIOS PHARMACEUTICALS INC AGIO 0.13%
100. ALUMIS INC ALMS 0.13%
101. AURINIA PHARMACEUTICALS INC AUPH 0.13%
102. MBX BIOSCIENCES INC MBX 0.13%
103. NOVOCURE LTD NVCR 0.13%
104. SUMMIT THERAPEUTICS INC ORDINARY SHARES SMMT 0.13%
105. XENCOR INC XNCR 0.13%
106. FORTREA HOLDINGS INC FTRE 0.12%
107. GRIFOLS SA ADR GRFS 0.12%
108. INTELLIA THERAPEUTICS INC NTLA 0.12%
109. n/a NUVB 0.12%
110. UROGEN PHARMA LTD URGN 0.12%
111. ANAPTYSBIO INC ANAB 0.11%
112. IMMUNOCORE HOLDINGS PLC ADR IMCR 0.11%
113. MINERALYS THERAPEUTICS INC MLYS 0.11%
114. n/a TSHA 0.11%
115. RECURSION PHARMACEUTICALS INC CLASS A RXRX 0.11%
116. STOKE THERAPEUTICS INC STOK 0.11%
117. SYNDAX PHARMACEUTICALS INC SNDX 0.11%
118. TREVI THERAPEUTICS INC TRVI 0.11%
119. COMPASS PATHWAYS PLC ADR CMPS 0.10%
120. INHIBRX BIOSCIENCES INC INBX 0.10%
121. NOVAVAX INC NVAX 0.10%
122. RAPPORT THERAPEUTICS INC RAPP 0.10%
123. VIR BIOTECHNOLOGY INC VIR 0.10%
124. ABSCI CORP ABSI 0.09%
125. ALTO NEUROSCIENCE INC ANRO 0.09%
126. GH RESEARCH PLC GHRS 0.09%
127. REPLIMUNE GROUP INC REPL 0.09%
128. KURA ONCOLOGY INC KURA 0.08%
129. LAKEFRONT BIOTHERAPEUTICS NV ADR LKFT 0.08%
130. MANNKIND CORP MNKD 0.08%
131. MESOBLAST LTD ADR MESO 0.08%
132. PRECIGEN INC PGEN 0.08%
133. STEVANATO GROUP SPA STVN 0.08%
134. TYRA BIOSCIENCES INC TYRA 0.08%
135. ARRIVENT BIOPHARMA INC AVBP 0.07%
136. CASTLE BIOSCIENCES INC CSTL 0.07%
137. CULLINAN THERAPEUTICS INC CGEM 0.07%
138. GERON CORP GERN 0.07%
139. JANUX THERAPEUTICS INC ORDINARY SHARES JANX 0.07%
140. MAZE THERAPEUTICS INC MAZE 0.07%
141. MEIRAGTX HOLDINGS PLC MGTX 0.07%
142. PERSONALIS INC PSNL 0.07%
143. PHARVARIS NV ORDINARY SHARES PHVS 0.07%
144. SEPTERNA INC SEPN 0.07%
145. ZENAS BIOPHARMA INC ZBIO 0.07%
146. ANNEXON INC ORDINARY SHARES ANNX 0.06%
147. ARBUTUS BIOPHARMA CORP ABUS 0.06%
148. BICARA THERAPEUTICS INC BCAX 0.06%
149. CORVUS PHARMACEUTICALS INC CRVS 0.06%
150. MONTE ROSA THERAPEUTICS INC GLUE 0.06%
151. n/a MRVI 0.06%
152. ORIC PHARMACEUTICALS INC ORIC 0.06%
153. RIGEL PHARMACEUTICALS INC RIGL 0.06%
154. THERAVANCE BIOPHARMA INC TBPH 0.06%
155. USD CASH n/a 0.06%
156. ACLARIS THERAPEUTICS INC ACRS 0.05%
157. ALVOTECH ALVO 0.05%
158. CANDEL THERAPEUTICS INC CADL 0.05%
159. IRONWOOD PHARMACEUTICALS INC CLASS A IRWD 0.05%
160. n/a OLMA 0.05%
161. n/a FDMT 0.05%
162. SANA BIOTECHNOLOGY INC ORDINARY SHARES SANA 0.05%
163. SOLID BIOSCIENCES INC SLDB 0.05%
164. WAVE LIFE SCIENCES INC WVE 0.05%
165. ZEVRA THERAPEUTICS INC ZVRA 0.05%
166. ALLOGENE THERAPEUTICS INC ALLO 0.04%
167. ALTIMMUNE INC ALT 0.04%
168. ARVINAS INC ARVN 0.04%
169. CYTEK BIOSCIENCES INC CTKB 0.04%
170. CYTOMX THERAPEUTICS INC CTMX 0.04%
171. DESIGN THERAPEUTICS INC DSGN 0.04%
172. n/a SGMT 0.04%
173. n/a PHAT 0.04%
174. NEUROGENE INC NGNE 0.04%
175. OMNIAB INC OABI 0.04%
176. OPKO HEALTH INC OPK 0.04%
177. REGENXBIO INC RGNX 0.04%
178. SAVARA INC SVRA 0.04%
179. ARCTURUS THERAPEUTICS HOLDINGS INC ARCT 0.03%
180. ARS PHARMACEUTICALS INC SPRY 0.03%
181. AURA BIOSCIENCES INC AURA 0.03%
182. AUTOLUS THERAPEUTICS PLC ADR AUTL 0.03%
183. BRIDGEBIO ONCOLOGY THERAPEUTICS INC BBOT 0.03%
184. C4 THERAPEUTICS INC ORDINARY SHARES CCCC 0.03%
185. CABALETTA BIO INC ORDINARY SHARES CABA 0.03%
186. EDITAS MEDICINE INC EDIT 0.03%
187. ENANTA PHARMACEUTICALS INC ENTA 0.03%
188. n/a CTNM 0.03%
189. PACIFIC BIOSCIENCES OF CALIFORNIA INC PACB 0.03%
190. PROTHENA CORP PLC PRTA 0.03%
191. ROCKET PHARMACEUTICALS INC RCKT 0.03%
192. SILENCE THERAPEUTICS PLC ADR SLN 0.03%
193. ANAVEX LIFE SCIENCES CORP AVXL 0.02%
194. ATEA PHARMACEUTICALS INC ORDINARY SHARES AVIR 0.02%
195. BIOAGE LABS INC BIOA 0.02%
196. BLACKROCK CASH FUNDS TREASURY SL AGENCY n/a 0.02%
197. EMERGENT BIOSOLUTIONS INC EBS 0.02%
198. FULCRUM THERAPEUTICS INC FULC 0.02%
199. FULGENT GENETICS INC FLGT 0.02%
200. GINKGO BIOWORKS HOLDINGS INC DNA 0.02%
201. IMMUNEERING CORP CLASS A IMRX 0.02%
202. KYVERNA THERAPEUTICS INC KYTX 0.02%
203. LEXEO THERAPEUTICS INC LXEO 0.02%
204. MYRIAD GENETICS INC MYGN 0.02%
205. PERSPECTIVE THERAPEUTICS INC CATX 0.02%
206. PRIME MEDICINE INC PRME 0.02%
207. STANDARD BIOTOOLS INC LAB 0.02%
208. TECTONIC THERAPEUTIC INC TECX 0.02%
209. UPSTREAM BIO INC UPB 0.02%
210. VANDA PHARMACEUTICALS INC VNDA 0.02%
211. AARDVARK THERAPEUTICS INC AARD 0.01%
212. AC IMMUNE SA ACIU 0.01%
213. ADC THERAPEUTICS SA ADCT 0.01%
214. ALPHA TEKNOVA INC TKNO 0.01%
215. BICYCLE THERAPEUTICS PLC ADR BCYC 0.01%
216. CARIBOU BIOSCIENCES INC ORDINARY SHARES CRBU 0.01%
217. CELLECTIS SA ADR CLLS 0.01%
218. CODEXIS INC CDXS 0.01%
219. ENTRADA THERAPEUTICS INC TRDA 0.01%
220. FOGHORN THERAPEUTICS INC ORDINARY SHARES FHTX 0.01%
221. GOSSAMER BIO INC GOSS 0.01%
222. HUMACYTE INC HUMA 0.01%
223. KEROS THERAPEUTICS INC KROS 0.01%
224. LARIMAR THERAPEUTICS INC LRMR 0.01%
225. LENZ THERAPEUTICS INC LENZ 0.01%
226. LINEAGE CELL THERAPEUTICS INC LCTX 0.01%
227. LYELL IMMUNOPHARMA INC ORDINARY SHARES LYEL 0.01%
228. n/a BDTX 0.01%
229. NEUMORA THERAPEUTICS INC NMRA 0.01%
230. NOVABRIDGE BIOSCIENCES ADR NBP 0.01%
231. PEPGEN INC PEPG 0.01%
232. PYXIS ONCOLOGY INC PYXS 0.01%
233. QUANTERIX CORP QTRX 0.01%
234. QUANTUM-SI INC ORDINARY SHARES CLASS A QSI 0.01%
235. SIONNA THERAPEUTICS INC SION 0.01%
236. TENAYA THERAPEUTICS INC TNYA 0.01%
237. VOYAGER THERAPEUTICS INC VYGR 0.01%
238. AKERO THERAPEUTICS CVR n/a 0.00%
239. AKOUOS CVRS PRVT n/a 0.00%
240. ARCELLX INC CVR n/a 0.00%
241. CARGO THERAPEUTICS INC n/a 0.00%
242. CARTESIAN THERAPEUTICS ([WTS/RTS]) 0% n/a 0.00%
243. CHINOOK THERAPEUTICS INC n/a 0.00%
244. E-MINI HEALTH CARE SECTOR SEP 26 n/a 0.00%
245. FUSION PHARMACEUTICALS INC CVR n/a 0.00%
246. IMMUTEP LTD ADR IMMP 0.00%
247. JYONG BIOTECH LTD MENS 0.00%
248. OMNIAB INC $12.50 VESTING PRVT n/a 0.00%
249. OMNIAB INC $15.00 VESTING PRVT n/a 0.00%
250. RUSSELL 2000 EMINI CME SEP 26 n/a 0.00%
251. THIRD HARMONIC BIO INC n/a 0.00%
Holdings data last updated Oct 8, 2026 5:20 AM .
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